What Is Scleroderma?

Scleroderma is arare autoimmune disorder made up of a group of diseases. There are 2 types of scleroderma: localized and systemic. Localized scleroderma affects primarily the skin. Systemic scleroderma affectsthe skin, as well as bloodvessels and internal organs.

Sclerodermacauses your body to produce too much collagen.Collagenis aproteinthat makes up connective tissues, such as the skin. When you have too much collagen, your skin can stretch, thicken, and harden. It also can cause damage to internal organs, such as the heart,lungs,and kidneys.

Symptoms of scleroderma

Within localized scleroderma, there are 2 forms:

With 1 form, symptoms start with red patches of skin that thicken into hard, oval-shaped areas. The patches later become white in the middle with purple borders. Patches often appear on your chest, stomach, and back, but also can occur on your face, arms, and legs. You may have 1 or more patches as small as half an inch or as large as 12 inches in diameter.
With the other form, the main symptom is a line or band of skin that thickens and changes color. This line can appear on your arm, leg, or forehead. Linear scleroderma is more common in children.

Within systemic scleroderma, there are 2 forms:

Limited scleroderma progresses gradually. It affects the skin on your fingers, hands, lower arms, legs, and face. It causes patches of skin to become thick and firm and change color. People who have this also may haveRaynaud’s disease or problems with frequent heartburn. Limited scleroderma also can affect your lungs,esophagus, and blood vessels.
Diffuse scleroderma progresses quickly. Symptoms include fatigue, loss of appetite, and joint swelling and pain. It can affect the skin all over your body, causing it to swell and become tight, shiny, and itchy. Over time, your skin may go back to normal. Diffuse scleroderma also can damage internal organs, such as your intestines, lungs, kidneys, and heart.

What causes scleroderma?

The exact cause of scleroderma is unknown. It occurs when your immune system attacks your body’s tissues and/or organs.

How is scleroderma diagnosed?

Your doctor will ask you about your symptoms and medical history. He or she also will perform a physical exam and look for changes in the appearance of your skin. Your doctor may want to remove a small sample of skin (biopsy) to look at it under a microscope. He or she also may order a blood test to check for antibodies, or other tests to see if any internal organs have been affected. All of this helps to determine if you have scleroderma.

Can scleroderma be prevented or avoided?

You can’t prevent or avoid scleroderma.

Scleroderma treatment

Your doctor will choose the right treatment for you depending on your type and symptoms. Treatment focuses on relieving symptoms and preventing more damage. Possible treatments include medicine, such as creams for your skin. He or she may also recommend dietary and lifestyle changes. Your doctor may suggest physical oroccupational therapyto help you manage your pain. Cosmetic surgery may help to lessen the effects of scleroderma on your skin.

Localized scleroderma sometimes goes away on its own. If scleroderma has caused internal damage, your doctor may work with specialists to treat your condition. For example, if scleroderma affects your heart, your doctor will work closely with a heart specialist (cardiologist).

Living with scleroderma

There is no cure for scleroderma. The best thing you can do is to work with your doctor(s) to manage symptoms and prevent complications. Plus, there are things you can do on your own that may help.

If you have skin problems, try to keep your skin soft and moisturized. Apply lotions often, wear sunscreen outside, and use a humidifier at home. Avoid harsh skin products, as well as hot showers and baths.

If you have heartburn or other digestive problems, try to eat small, frequent meals. Don’t lay down right after eating. Avoid spicy foods, alcohol, caffeine, and other things that trigger heartburn.

If you have Raynaud’s disease, you can relieve symptoms by:

Not smoking
Wearing warm clothes, including socks and gloves, if needed
Doing regular exercise
Avoiding things that cause increased stress or anxiety

Talk to your doctor about other ways to help improve blood flow, including medicine. He or she also may prescribe medicines to treat skin patches, sores, and lesions.

Be sure to contact your doctor if you have new or worsening symptoms or health problems.